Chelsea midfielder N'Golo Kante is out of their clash at Ajax in the Champions League.
Blues attacker Ross Barkley will also miss the game.
The pair of midfielders missed the final training session on Tuesday morning in Cobham ahead of the flight to Amsterdam after failing to recover in time from their injuries.
Barkley limped off before half-time against Newcastle on Saturday after damaging his ankle. Kante, meanwhile, has been out since picking up a groin injury while on international duty with France.
Chelsea were handed a boost as defender Emerson Palmieri took part in the session, warming up with his team-mates before doing some ball work, reports the Daily Mail.
