Southampton boss Ralph Hasenhuttl will manage Tuesday's game against West Ham from home after a member of his household tested positive for coronavirus, reports BBC Sport.
The club said the 53-year-old "is currently self-isolating while we assess the situation further".
Hasenhuttl will contact the team and coaching staff throughout the game via a video and audio link.
Southampton made the announcement three hours and 15 minutes before kick-off.
