Tottenham will host champions Manchester City on the opening weekend of the new Premier League season.
Chelsea boss Thomas Tuchel, meanwhile, faces a nightmare start to his first full campaign in charge of Chelsea, with trips to three 'Big Six' rivals in the first five matches.
In the first round of fixtures in mid-August, City's trip to north London is the stand-out game.
Elsewhere on the opening weekend, Manchester United host Leeds, Liverpool travel to newly-promoted Norwich and Chelsea host a London derby against Crystal Palace.
2021-22 OPENING WEEKEND FIXTURES
Burnley v Brighton
Leicester City v Wolverhampton
Manchester United v Leeds United
Newcastle United v West Ham United
