Tottenham boss Nuno faces being without seven players for this weekend's Premier League return.
They're guaranteed to be without Giovani Lo Celso, Cristian Romero and Davinson Sanchez after they jetted off to South America.
All three players are currently completing a 10-day stint in isolation.
Another player that could miss Tottenham's game against Palace is Heung-Min Son after picking up a calf injury on international duty.
Son was left out of South Korea's squad for the game against Lebanon on Tuesday as a precaution and his knock is thought to be only minor.
There's also a good chance Nuno will be without England U21 star Oliver Skipp, who picked up a knock in the 2-0 win against Kosovo on Tuesday.
The midfielder limped out of the match with groin injury, just a day after Ryan Sessegnon suffered a 'knock' in training.
The final headache for Nuno is Steven Bergwijn, who limped out of Holland's 6-1 win against Turkey in World Cup qualifying on Tuesday.
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