Pedri and Ousmane Dembele are out of Barcelona's derby clash with Espanyol.
Neither took part in training on Thursday and will, as such, be out of action this weekend.
The Catalans will train again on Friday, but one session alone won't be enough to have them available for the weekend.
Now it remains to be seen if they'll be back in time for Tuesday's Champions League meeting with Benfica, which Barcelona know they will have to win as a defeat would risk ending their hopes of progressing to the knockout rounds of Europe's elite club competition.
The derby on Saturday will be Xavi's first as Barca coach.
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