Manchester City defender Ruben Dias has been ruled out for the remainder of the season.
Dias limped out at half-time of Sunday's five-goal mauling of Newcastle United after suffering a hamstring problem.
Pep Guardiola confirmed that Dias, Kyle Walker and John Stones will play no further part this season as City look to stave off Liverpool and clinch a fourth Premier League crown in five years.
Nathan Ake was named on the bench on Sunday but his persistent ankle problem is likely to see the Holland international miss Wednesday's visit to Wolves, described by Guardiola as a 'final final'. Club captain Fernandinho is set to deputise.
"We have 13-and-a-half players available for these games, no more than that," the City manager said. "When that happens everyone has to do more and more to help with the absence. It is what it is. We arrive with problems and that's all.
"But honestly in this situation it's not a problem. If Rodri has to play in that position he will play. Everyone has to do extra."
Need a VPN? Or seeking to switch? Then support Tribal Football by clicking here to sign up with our official partners NordVPN. Not only will you receive the best VPN experience, but also great discounts by signing up via Tribal Football. Thanks for your support!