Barcelona face being without defenders Jules Kounde and Ronald Araujo for the comng weeks.
Having been forced off in Uruguay's friendly defeat to Iran on Friday, Araújo on Saturday underwent tests that confirmed the 23-year-old has suffered a serious groin injury.
AS reports he faces as long as six to seven weeks on the sidelines, ruling him out of almost all Barça's remaining games in 2022.
Among the matches Araújo is set to miss are next month's Clásico against Real Madrid, and the rest of the Blaugrana's fixtures in this season's Champions League group stage, which concludes at the start of November.
Koundé appears certain to miss Barça's next four games, which include a Champions League double header against Inter Milan, but the former Sevilla player has an outside chance of making it back in time for his team's matchup with arch rivals Real Madrid on 16 October.
