Barcelona have released statements on the injuries for Frenkie de Jong and Pedri.
Both players broke down during the draw at Athletic Bilbao on Sunday.
Dutchman De Jong has suffered a sprain of the external lateral ligament of his right ankle, while Canary Islander Pedri damaged the rectus femoris of his right thigh.
Pedri's injury is his third suffered this season.
Inside Barca, there's now fears neither player will be fit for the second-leg of their Champions League round 16 tie with Napoli.