- Amy Madigan secured the Best Supporting Actress Oscar for her role in Weapons at the 98th Academy Awards in Los Angeles.
- In Weapons, a supernatural horror film, she portrayed the character of Aunt Gladys, whose striking appearance became an internet meme.
- During her acceptance speech, Madigan expressed gratitude to her family, including her daughter Lily, son-in-law Sean, and her husband Ed Harris.
- Her victory established a new record for the longest interval between an Oscar nomination and a win, spanning 40 years.
- Madigan was previously nominated in the same category in 1986 for her performance in Twice in a Lifetime.
