Champions League title holders Manchester City will meet FC Copenhagen in the round of 16.
Today's UEFA draw has also paired Arsenal with Porto, while Real Madrid meet RB Leipzig and last season's runners-up Inter Milan will face Atletico Madrid.
The first legs take place on 13-14 or 20-21 February and the second on 5-6 or 12-13 March.
Champions League Last-16 draw
Porto v Arsenal
Napoli v Barcelona
Paris St-Germain v Real Sociedad
Inter Milan v Atletico Madrid
PSV Eindhoven v Borussia Dortmund
Lazio v Bayern Munich
Copenhagen v Manchester City
RB Leipzig v Real Madrid