The Toffees returned to England after two disappointing defeats in the United States with no goals scored and six conceded.
Vitalii Mykolenko and Tom Davies scored for Everton in the first 11 minutes.
Championship side Blackpool pulled one back before half-time through Gary Madine.
Alli then scored on both sides of Callum Connolly's goal for Blackpool.
Need a VPN? Or seeking to switch? Then support Tribal Football by clicking here to sign up with our official partners NordVPN. Not only will you receive the best VPN experience, but also great discounts by signing up via Tribal Football. Thanks for your support!