- A new study suggests that frequent consumption of anticholinergic drugs, prescribed for conditions including chronic obstructive pulmonary disease and Parkinson’s, may lead to faster ageing in older adults.
- Published in JAMA Open Network, the research indicates that high exposure to these medications is linked to an “accelerated decline” in physical performance.
- The study, which monitored over 4,000 older adults, found a significant association between higher anticholinergic exposure and a greater reduction in walking speed.
- Anticholinergic drugs block the action of acetylcholine, a key nerve-to-nerve signalling molecule, affecting various bodily functions.
- Researchers are calling for the minimisation of anticholinergic drug prescriptions to promote healthy ageing, advising clinicians to avoid their use when possible and to re-evaluate patients regularly.
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