Hormone-free male contraceptive pill passes human trial

TechnologyHealth & Fitness
5 Aug 2025 • 9:05 PM MYT
The Independent
The Independent

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  • A new hormone-free male contraceptive pill, YCT-529, has demonstrated safety in early-stage clinical trials.
  • Developed by YourChoice Therapeutics, the drug works by blocking vitamin A metabolites to prevent sperm production without impacting sex hormones.
  • The trial, involving 16 male volunteers, reported no adverse side effects, including on cardiac health, hormone levels, or mood.
  • The innovation offers a potential alternative to existing male contraception.
  • While hailed as an "exciting step forward", experts highlight the need for further testing to confirm the pill’s efficacy in preventing pregnancy and to address market costs.

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