More than 80,000 people have left Rafah since Monday as Israeli continues its offensive in southern Gaza, the UN has said.
Most of those uprooted by Israeli military evacuation orders in eastern Rafah have already been displaced from other areas of Gaza, according to the UN agency for Palestinian refugees (UNRWA).
The agency said people people were leaving with everything they can carry “in vehicles, trucks, (on) motorbikes and donkey carts”.
Shelling has been reported in Rafah overnight, just hours after US president Joe Biden publicly vowed to withhold weapons from Israel if its forces make a ground offensive into southern Gaza.
“I made it clear that if they go into Rafah ..., I’m not supplying the weapons,” Mr Biden, whose administration has repeatedly asked Israel for its plan to protect civilians in Rafah, said in an interview with CNN.
There was no immediate comment from Israel on Mr Biden’s remarks, but Israeli prime minister Benjamin Netanyahu has vowed the Rafah operation will go ahead, saying it must hit Rafah to defeat Hamas fighters there.