Manchester United shot stopper Andre Onana could miss up to seven games this season.
The Cameroonian had previously retired from international football, but has changed his mind.
The 27-year-old and his Cameroon side face an AFCON qualifier against Burundi during this international break.
Should they progress to AFCON, then Onana would be absent in January and February.
Onana would be absent from Premier League matches against Tottenham, Wolves, West Ham and Aston Villa.
He would also miss both Carabao Cup semi final legs, should United make it that far.