Manchester United captain Bruno Fernandes is out of next Sunday's clash at Liverpool.
Fernandes will be suspended after being booked during defeat to Bournemouth.
He appeared to receive the caution for dissent, from referee Peter Bankes. It marked his fifth yellow card and triggers an automatic one match suspension.
Fernandes had been walking the disciplinary tightrope for a number of weeks, with the bookings he had received coming before the end of October.