New test cuts chance of late-stage ovarian cancer

Health & Fitness
30 Sep 2025 • 1:35 PM MYT
The Independent
The Independent

The world’s most free-thinking newspaper

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  • University College London Hospitals (UCLH) is the first in England to implement a new ovarian cancer surveillance test, Roca, for women with an inherited risk of the disease.
  • The Roca test is designed for women with BRCA1 or BRCA2 gene mutations, who face a significantly higher risk of developing ovarian cancer.
  • This blood test, taken every four months, calculates an individual's risk by tracking changes in CA 125 protein levels over time, even within normal ranges.
  • It dramatically cuts the chance of being diagnosed with late-stage ovarian cancer, offering an alternative to immediate preventative surgery, which can lead to early menopause or prevent future childbearing.
  • Professor Adam Rosenthal of UCLH expressed hope for a national programme to ensure all women with BRCA mutations can access this test, preventing a postcode lottery of care.

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