Revolutionary test spares millions of cancer patients from chemotherapy

Health & Fitness
30 May 2026 • 2:47 PM MYT
The Independent
The Independent

The world’s most free-thinking newspaper

Revolutionary test spares millions of cancer patients from chemotherapy

  • A revolutionary genomic test, Prosigna, could spare millions of breast cancer patients from chemotherapy, a clinical trial has shown.
  • The Optima trial observed over 4,400 women and men aged 40 or older with hormone-sensitive breast cancer, who would typically receive chemotherapy.
  • Participants with a low Prosigna score, indicating low gene activity, were treated with hormone therapy alone.
  • Those with high scores received chemotherapy and hormone therapy.
  • Results showed that five years after treatment, 93.6 per cent of low-scoring patients treated with hormone therapy alone were alive and recurrence-free, comparable to the 94.8 per cent who also received chemotherapy.

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