- New research has identified specific structural changes within lymph nodes that can predict the likelihood of breast cancer spreading.
- These changes in the lymph node's intricate network, specifically involving fibroblastic reticular cells (FRC), can occur even before cancer cells are visible.
- The study found that some structural shifts were linked to improved survival chances, while others indicated a worse prognosis, offering insights for tailored treatment.
- Funded by Breast Cancer Now, these findings could lead to more personalised treatment decisions, potentially helping patients avoid unnecessary lymph node removal and associated side effects like lymphoedema.
- Experts believe this research could help identify individuals at higher or lower risk of breast cancer progression, paving the way for new targeted therapies.
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