Using certain type of HRT before menopause could raise cancer risk - study

Health & Fitness
1 Jul 2025 • 2:34 PM MYT
The Independent
The Independent

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  • An international study examined the link between hormone replacement therapy (HRT) and young-onset breast cancer in women aged 16 to 54.
  • The research found that overall HRT use was not broadly connected to an increased risk of young-onset breast cancer.
  • However, oestrogen-only hormone therapy appeared to decrease breast cancer risk by 14 per cent in younger women.
  • Conversely, oestrogen plus progestin therapy was associated with a 10 per cent increased risk of young-onset breast cancer.
  • These findings offer new guidance for clinical recommendations on HRT use in younger women, where previous information was limited.

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