What do statins do? Everything to know about the cholesterol medication

Health & Fitness
6 Feb 2026 • 7:18 PM MYT
The Independent
The Independent

The world’s most free-thinking newspaper

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  • New research published in The Lancet indicates that most commonly reported side effects of statins, such as depression and headaches, are not directly caused by the medication.
  • Statins are medicines that lower 'bad' cholesterol (LDL) and triglyceride levels, which helps prevent plaque build-up in arteries and reduces the risk of heart attacks and strokes.
  • GPs prescribe statins based on a comprehensive risk calculation for cardiovascular disease, considering factors like family history, blood pressure, and weight, not solely high cholesterol levels.
  • While generally safe, statins may not be suitable for everyone, particularly those with liver or kidney problems, certain allergies, or during pregnancy, necessitating discussion with a GP.
  • Statins are typically a lifelong medication, usually taken once daily, and their effectiveness is significantly enhanced when combined with a healthy lifestyle, including diet and exercise.

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