Newcastle winger Allan Saint-Maximin and captain Jamaal Lascelles are both suffering from the long-term effects of coronavirus and it is not known when they will return.
The pair were among several players to have contracted the virus when an outbreak hit the club earlier this month.
That forced the postponement of Newcastle's game against Aston Villa and the training ground was closed for over a week.
The club only named the players after reports the duo were absent due to a falling out with boss Steve Bruce.
