Tottenham and Aston Villa have lost a battle to ensure their Argentina stars come home early during the international break.
Players going to South American countries must quarantine when they return to the UK, per COVID-19 protocols.
That means players missing one or two club games on their return, which teams such as Villa and Spurs wanted to avoid after this break.
Argentina manager Lionel Scaloni says his Premier League players will stay for all their World Cup Qualifying matches.
He said: "We are not going to do the same as last time with the Premier League players.
"Before the game with Venezuela I said that they came to play all three games but the players raised a difficult decision for me and I understood it, I released them.
"Now the players are here to play the three games. Under no point of view they will leave earlier."
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