- Andre Esterhuizen will captain South Africa for the first time in a one-off Test match against Australia in Perth.
- Springboks head coach Rassie Erasmus has made 13 changes to the starting line-up that defeated New Zealand in Baltimore.
- Handre Pollard returns to the starting XV after recovering from an injury that kept him out of the New Zealand series.
- Jasper Wiese is named among the replacements and is set to earn his 50th cap for the national side.
- The match serves as South Africa's final fixture before a month-long break ahead of their Nations Championship matches in November.
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