The British quartet of Dina Asher-Smith, Imani Lansiquot, Amy Hunt and Daryll Neita secured women’s 4×100 metres silver at the Stade de France.
Team GB won bronze in the same event for the last two Olympics and were one of the favourites on Friday night.
They looked like they might be on course to secure gold before a messy handover between Hunt and anchor Neita cost them time.
The United States’ Sha’Carri Richardson took full advantage to pip the Brits to the line by seven one hundredths of a second in 41.78.