Tottenham boss Ange Postecoglou is confident they can handle their international absentees.
Yves Bissouma and Pape Matar Sarr are leaving for the Africa Cup of Nations, while Heung-min Son will be part of the Asian Cup.
Postecoglou has dismissed claims they may avoid African and Asian players in the future due to the midseason tournaments.
I'd hate for that to be the case because you'd miss out on some fantastic talent," said Postecoglou.
"We've got a generational player from Asia that's been representing our club. If we lose him every four years for five weeks, I think it's a real small price to pay.
"I love international football, I think it's important. I don't like the way the calendar has been crammed, but the tournaments they are going to now are significant tournaments. They're not sort of just thrown together in the last couple of years.
"The African Cup of Nations is very important and the Asia Cup is very important for these nations. You've got to understand these guys, this is where they were brought up. This is where a lot of who they are today comes from and when they go and represent their country and put their shirt on, it's not just another game of football for them. So I'm sure Sonny and Pape would have loved to have been here with us, but it doesn't diminish what they do there.
"I would never rule out somebody because they're going to represent their country. I think representing your country helps a player develop both professionally and personally."
