Real Madrid president Florentino Perez has put Isco up for sale.
Mundo Deportivo says ahead of the January market, Florentino has had Isco's availability circulated across Europe.
And he has already fielded enquiries from Tottenham, Juventus and Napoli.
The president has also already set his terms, insisting the bidding begin at 70m.
Manchester City are also expected to be in touch given management's admiration of Isco.
